The ASCL1 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to ASCL1, HASH1, MASH1, and zASIC2. This antibody recognizes Human antigen. The ASCL1 Antibody (N-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the basic helix-loop-helix
(BHLH) family of transcription factors. The protein activates
transcription by binding to the E box (5'-CANNTG-3'). Dimerization
with other BHLH proteins is required for efficient DNA binding.
This protein plays a role in the neuronal commitment and
differentiation and in the generation of olfactory and autonomic
neurons. Mutations in this gene may contribute to the congenital
central hypoventilation syndrome (CCHS) phenotype in rare cases.